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Subject: [gsp-l] Re: [gsp-l] ofa policy and comment
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Tracy NovoaUser is Offline
Western NY
MH
MH
Posts:191


11/04/2011 8:17 AM  
Since this is not a marker-based test but has been a gene-based test for a YEAR now, is the Univ. Of PA going to update OFA so our 1ST round of test submissions are not published as "probable normal"?

Why was this at least not known by the NSS when the clinic was provided? No need to answer, just seems like valuable info was not disclosed properly...until last night.

Sent from my Verizon Wireless Phone

----- Reply message -----
From: "Leita Estes"
To: "gsp list"
Subject: [gsp-l] ofa policy and comment
Date: Wed, Sep 14, 2011 12:39 pm


OFA Clear By Parentage Policy

As a greater number of DNA based disease tests become available, a policy regarding the clearing of offspring out of DNA tested parents has become necessary.
For direct mutant gene tests only, the OFA will issue clearances to untested offspring:
  • If the sire and dam have both been DNA tested “Clear,”
  • If the sire and dam’s DNA disease test results have been OFA registered, and
  • If all three (sire/dam/offspring) have been DNA identity profiled and parentage verified.
The DNA profile paperwork must be submitted along with a completed OFA DNA-based disease test application. The resulting OFA certification will have a suffix of “CBP” (clear by parentage), indicating that the dog itself was not tested and that the clearance was based on the sire and dam’s test results, and known science at the time. Because of the possibility of new mutations or as of yet undiscovered gene mutations, only first generation offspring will be cleared.
For linkage or marker based tests where a margin of error including both false positives and negatives exists, the OFA will not issue any clearances to untested dogs.
DNA based disease screening is an evolving area. This policy is subject to change by action of the OFA Board of Directors as technology and science advance.
 
OFA reviews this policy yearly and is committed to doing the best for our dogs and breeding programs. They will need to collect many generations of tested offspring to be sure there aren't any mutations or even more of a possibility a new discovery of another gene involved in expression. They might never change this policy so we need to embrace it and just go with it.  I think the reason people want all generations cleared is personal and maybe a bit selfish as they don't want to spend the money on the tests. As I stated before my personal policy is to clear all breeding stock not all pet puppies. If I clear every generation of the dogs I breed then all puppies are cleared by parentage. If you are breeding a carrier to a clear that is a different situation and you should clear each pup that will be used for breeding so the new owner will be able to make an informed decision about buying the puppy. Since carrier status has nothing to do with the health of a pet puppy there really isn't a reason to test the pets.

Leita Estes Shortales German Shorthaired Pointers
Home of Multiple BIS, BISS GCh Shortales N Cahoots W Irondale, JH
# 1 GSP 2011
1 Spotty dog (Dalmatian) Ch. Merry Go Rounds Match Point

Enjoy them every minute you have them!
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Forums > Mailing Lists > gsp-l > [gsp-l] Re: [gsp-l] ofa policy and comment



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